Conn's syndrome, also known as primary aldosteronism (PA), is one of the most common underlying causes of Hypertension, with a 5% - 22% prevalence and is associated with a higher incidence of co-morbidities, compared to patients with essential hypertension with similar blood pressure. It is a treatable and, in the case of unilateral primary aldosteronism, curable disease. Yet, fewer than 1% of patients with primary aldosteronism are diagnosed. Diagnosis is time-consuming due to the need for specialist tests. Increasing rates of diagnosis is, therefore, vital in improving patient outcomes.
Patients under the secondary hypertension clinic, if confirmed to have unilateral (one sided) Conn’s syndrome has the potential to participate in WAVE trial.
The other common secondary causes of Hypertension/ multi-drug-resistant hypertension are Obstructive sleep apnoea, Renal artery stenosis (narrowing) and kidney disease.
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